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Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387955429ISBN 13: 9780387955421
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -An eminent scientist talks about the pharmaceutical industry, biotechnology and the future of drug research. In the course of our busy, technologically-driven lives, it is taken for granted that we respond to minor fluctuations in our health by taking pills- pills for headache and for toothache; sleeping pills and tranquilizers; pills to lower fever, quiet coughs, and clear the sinuses; medicines to reduce appetite; preparations to relieve heartburn; and many more. In the war against serious disease, medicines are an indispensable weapon in the physician's arsenal: they save lives, or at least prolong them and make them more bearable. Despite the important role that pharmaceuticals play in our lives, few of us know where medicines come from or how the pharmaceutical industry discovers and develops new drugs. Jürgen Drews, an acclaimed leader in the pharmaceutical industry, tells the fascinating story of drug discovery and development from his years of successfully leading international research teams at Hoffman-LaRoche. Drews traces the history of modern drug development from pharmacies, chemical companies, and individual entrepreneurs in Switzerland, Germany and the U.S. to the mega-corporations that dot the landscape of Europe, Japan and America. He describes the process by which new drugs are tested and brought to market, including a provocative look at how AIDS activism stimulated the approval process in the U.S. Drews' commentary on the role of clinical trials- the time involved and their cost- is sobering testimony to the complexity of bringing innovation to the marketplace. In the final two chapters of 'In Quest of Tomorrow's Medicines', Drews offers an important and critical analysis of research inthe pharmaceutical industry, pointing to strategies that work and management practices that impede progress. 280 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387001387ISBN 13: 9780387001388
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -By providing a comprehensive look at statistical inference from record-breaking data in both parametric and nonparametric settings, this book treats the area of nonparametric function estimation from such data in detail. Its main purpose is to fill this void on general inference from record values. Statisticians, mathematicians, and engineers will find the book useful as a research reference. It can also serve as part of a graduate-level statistics or mathematics course. 128 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 038795547XISBN 13: 9780387955476
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -More mathematicians have been taking part in the development of digital image processing as a science and the contributions are reflected in the increasingly important role modeling has played solving complex problems. This book is mostly concerned with energy-based models. Most of these models come from industrial projects in which the author was involved in robot vision and radiography: tracking 3D lines, radiographic image processing, 3D reconstruction and tomography, matching, deformation learning. Numerous graphical illustrations accompany the text. 340 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387955844ISBN 13: 9780387955841
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Aimed at undergraduate mathematics and computer science students, this book is an excellent introduction to a lot of problems of discrete mathematics. It discusses a number of selected results and methods, mostly from areas of combinatorics and graph theory, and it uses proofs and problem solving to help students understand the solutions to problems. Numerous examples, figures, and exercises are spread throughout the book. 308 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387954716ISBN 13: 9780387954714
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Researchers in many disciplines face the formidable task of analyzing massive amounts of high-dimensional and highly-structured data. This is due in part to recent advances in data collection and computing technologies. As a result, fundamental statistical research is being undertaken in a variety of different fields. Driven by the complexity of these new problems, and fueled by the explosion of available computer power, highly adaptive, non-linear procedures are now essential components of modern 'data analysis,' a term that we liberally interpret to include speech and pattern recognition, classification, data compression and signal processing. The development of new, flexible methods combines advances from many sources, including approximation theory, numerical analysis, machine learning, signal processing and statistics. The proposed workshop intends to bring together eminent experts from these fields in order to exchange ideas and forge directions for the future. 488 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387951598ISBN 13: 9780387951591
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Medical Data Management is a systematic introduction to the basicmethodology of professional clinical data management. It emphasizesgeneric methods of medical documentation applicable to such diversetasks as the electronic patient record, maintaining a clinical trialsdatabase, and building a tumor registry. This book is for all studentsin medical informatics and health information management, and it isideal for both the undergraduate and the graduate levels. The bookalso guides professionals in the design and use of clinicalinformation systems in various health care settings. It is aninvaluable resource for all health care professionals involved indesigning, assessing, adapting, or using clinical data managementsystems in hospitals, outpatient clinics, study centers, health plans,etc.The book combines a consistent theoretical foundation of medicaldocumentation methods outlining their practical applicability in realclinical data management systems. Two new chapters detail hospitalinformation systems and clinical trials. There is a focus on theinternational classification of diseases (ICD-9 and -10) systems, aswell as a discussion on the difference between the two codes. Allchapters feature exercises, bullet points, and a summary to providethe reader with essential points to remember. New to the Third Editionis a comprehensive section comprised of a combined Thesaurus andGlossary which aims to clarify the unclear and sometimes inconsistentterminology surrounding the topic. 224 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387954104ISBN 13: 9780387954103
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book introduces the main topics of modern numerical analysis: sequence of linear equations, error analysis, least squares, nonlinear systems, symmetric eigenvalue problems, three-term recursions, interpolation and approximation, large systems and numerical integrations. The presentation draws on geometrical intuition wherever appropriate and is supported by a large number of illustrations, exercises, and examples. 364 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387954791ISBN 13: 9780387954790
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fundamentals of Family Medicine, Third Edition, describes the current approach to common problems in family practice. The book tells how family physicians provide high-quality, comprehensive, and ongoing health care for patients and families, based on current evidence and time-tested methods in clinical practice.Clinical scenarios that include case studies and questions for group discussion reinforce the book's clinical topics. The clinical scenarios all concern members of the Nelson family- a multigenerational extended family whose members visit the family physician with a variety of health concerns and whose dynamics evolve from chapter to chapter. The discussion questions allow the group to consider both the biomedical and psychosocial aspects of problems such as headache, obstructive airway disease, diabetes mellitus, athletic injuries, domestic violence, care of the dying patient, and the family physicians's role in dealing with terrorist events.The book is intended to be a reference source for the care of diseases family physicians are likely to see and as the course textbook for medical students in family medicine clerkships in medical school. This book will help health professionals provide up-to-date care for their patients, and will allow students to view clinical issues through the eyes of the family physician.Fundamentals of Family Medicine, Third Edition, ideally is used as a companion to Family Medicine: Principles and Practice, Sixth Edition, edited by Robert B. Taylor et al. 628 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387952284ISBN 13: 9780387952284
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This richly illustrated third edition provides a thorough training in practical mathematical biology and shows how exciting mathematical challenges can arise from a genuinely interdisciplinary involvement with the biosciences. It has been extensively updated and extended to cover much of the growth of mathematical biology.From the reviews: ''This book, a classical text in mathematical biology, cleverly combines mathematical tools with subject area sciences.'--SHORT BOOK REVIEWS 844 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387955461ISBN 13: 9780387955469
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Digital sky surveys, high-precision astrometry from satellite data, deep-space data from orbiting telescopes, and the like have all increased the quantity and quality of astronomical data by orders of magnitude per year for several years. Making sense of this wealth of data requires sophisticated statistical techniques. Fortunately, statistical methodologies have similarly made great strides in recent years. Powerful synergies thus emerge when astronomers and statisticians join in examining astrostatistical problems and approaches.The book begins with an historical overview and tutorial articles on basic cosmology for statisticians and the principles of Bayesian analysis for astronomers. As in earlier volumes in this series, research contributions discussing topics in one field are joined with commentary from scholars in the other. Thus, for example, an overview of Bayesian methods for Poissonian data is joined by discussions of planning astronomical observations with optimal efficiency and nested models to deal with instrumental effects.The principal theme for the volume is the statistical methods needed to model fundamental characteristics of the early universe on its largest scales. 532 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387955127ISBN 13: 9780387955124
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There is no dearth of books on telescope optics and, indeed, optics is clearly a keyelementinthedesignandconstructionoftelescopes.Butitisbynomeans the only important element. As telescopes become larger and more costly, other aspects such as structures, pointing, wavefront control, enclosures, and project management become just as critical. Although most of the technical knowledge required for all these elds is available in various specialized books, journal articles, and technical reports, they are not necessarily written with application to telescopes in mind. This bookisa rstattemptatassemblinginasingletextthebasicastronomicaland engineering principles used in the design and construction of large telescopes. Itsaimistobroadlycoverallmajoraspectsofthe eld,fromthefundamentals ofastronomicalobservationto optics, controlsystems,structural,mechanical, andthermalengineering,aswellasspecializedtopicssuchassiteselectionand program management. This subject is so vast that an in-depth treatment is obviously imprac- cal. Our intent is therefore only to provide a comprehensive introduction to the essential aspects of telescope design and construction. This book will not replace specialized scienti c and technical texts. But we hope that it will be useful for astronomers, managers, and systems engineers who seek a basic understanding of the underlying principles of telescope making, and for s- cialists who wish to acquaint themselves with the fundamental requirements and approaches of their colleagues in other disciplines. 536 pp. Englisch.
Publicado por Springer New York Jan 2003, 2003
ISBN 10: 0387952012ISBN 13: 9780387952017
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This user-friendly definitive reference work presents the full spectrum of current cancer treatment options available to the practicing general surgeon or trainee. Through the pairing of 4-color algorithms and concise, clinically oriented text, the reader can quickly visualize and understand the decision-making process. Separate algorithmic branches highlight surgical treatment, adjuvant therapies such as chemotherapy and radiation therapy, as well as combined modality treatment. Over 90 chapters address organ systems from head to toe and tackle special topics, including oncologic emergencies and diagnostic and therapeutic challenges, and surgical adjuncts. More than 200 illustrations augment the textbook. 812 pp. Englisch.